Influence of the lactic acid product “Nariné” on the intestinal microflora of the newborn in the early neonatal period


Armenian NIC on maternal and child health protection

In recent years, the number of diseases caused by micro-organisms from the conditional-pathogenic group has increased, which is related to the introduction of broad spectrum antibiotics into practice and the disruption of environmental relationships. For the purpose of prophylaxis of cannabis-septic diseases the method of artificial biocenoses has been successfully applied. We are interested in the influence of the lactic acid bacteria strain 317/402 in the form of the product “Nariné” on the formation of newborn intestinal biopsy in the early neonatal period. For this purpose a bacteriological study of the stools of 40 newborns from the main (22) and control (18) groups was conducted on days 1-3-4 and 5-6 of their life.

The children in the main group received “Nariné” from the 1st to the 6th day of their life 10-20 ml 5-6 times before breastfeeding. On 3-4 days of life in 4 newborns, Clesbisella Pneumonia (10 – 1 KOE) was shown, in 3 – Clepsiella Oxytoca (101 KOE), in 1 – E coli (10 – 1 KOE). In 14 (63.6%) of the newborn colonization of conditionally pathogenic microflora did not occur. At 5-6 days of life, bacteriological tests revealed Aquinobacteria (10 – 1 KOE) at 2, Enterobacteriaceae (10 ± 1 KOE) – at 1 E. coli (10 ± 1 KOE) – at 1. On 5-6 days of life, intestines were settled at 4 (18.1%), and the colonization did not exceed 10-KI, which in practice did not endanger the development of infectious disease.

Bacteriological studies carried out in 18 newborns in the control group at 3-4 days of life revealed Clesbell Pneumonia (103 KOE) – at 2 Kl Oxytoca (103 KDe) – at 1, Kibrobacteria (103 kDe) – at 1, Ps .Mibrabilis (103 KOE) – at 1, E. coli (103 KOE) – in 1 child. At 5-6 days of life, bowel colonization quality was the same, and a quantitative increase was observed in 2 newborns (Kane Penevonia – 105 KOE and Oxytoca – 105 KOE). Guts in 9 (50%) newborns were colonized with conditionally pathogenic microflora.

Thus, the lactic acid product “Nariné” influences the qualitative and quantitative composition of the intestinal microflora and its first day of life may prevent the colonization of a conditionally pathogenic microflora in the intestine, thus contributing to the prevention of infectious intestinal diseases in the newborn .